October 13, 20223 yr 2 minutes ago, HazletonEagle said: Oh wow.... President Biden erroneously said that his son, Beau, "lost his life in Iraq" during a speech in Colorado on Wednesday. "I say this as a father of a man and won the Bronze Star, the conspicuous service medal, and lost his life in Iraq," Biden said. Beau died of brain cancer in 2015. He's repeatedly claimed that the burn pits give Beau brain cancer, but I'm not sure there's much of a causal link there. I think it was just super ishy luck.
October 13, 20223 yr Author 18 minutes ago, we_gotta_believe said: He's repeatedly claimed that the burn pits give Beau brain cancer, but I'm not sure there's much of a causal link there. I think it was just super ishy luck. It seems to be well within the realm of possibility; they just don't have enough documentation to prove it: Quote A potential association with cancer is more tenuous, both experts said, since Iraq and Afghanistan veterans were exposed to burn pits within the last two decades or so, and some cancers aren't diagnosed until longer after exposure to a carcinogen. "There have been widespread reports of veterans coming down with rare cancers," Coughlin said. But "it may take decades — 30, 40, 50 years — before some chronic diseases manifest themselves." ... Coughlin said that of the various compounds soldiers were exposed to, dioxins are a particular concern because of a link to respiratory cancer. "Humans were not designed to deal with exposure to dioxins," he said. "There’s no safe exposure limit." However, establishing a casual link between burn pits and disease can be challenging, Savitz said, because exposures weren't well documented by the military. He is currently studying whether people with respiratory or cardiovascular diseases were previously stationed at bases that used burn pits. https://www.nbcnews.com/health/health-news/burn-pits-veterans-healthcare-risks-cancers-respiratory-illness-rcna40669
October 13, 20223 yr 1 hour ago, ToastJenkins said: Nah Lol, half this forum is a bunch of insecure pansies. You included.
October 13, 20223 yr 4 minutes ago, EaglesRocker97 said: It seems to be well within the realm of possibility; they just don't have enough documentation to prove it: Lung, skin, liver cancers? Sure. But brain cancer is a tougher link to establish.
October 13, 20223 yr 31 minutes ago, EaglesRocker97 said: So you dont understand the difference between Begrudge and Respect? So in your (and WGB) limited capacity, if you do not begrudge someone, then you have to respect them? begrudge bĭ-grŭj′ transitive verb To envy (someone) the possession or enjoyment of (something). To give or expend with reluctance. To grudge; to envy the possession of. respect rĭ-spĕkt′ transitive verb To feel or show deferential regard for; esteem or admire. To avoid interfering with or intruding upon. To avoid violating.
October 13, 20223 yr 8 minutes ago, EaglesRocker97 said: If people don't have any money, why is demand so high? Bingo. Consumption is at an all time high. People complain that they have no money while spending a few grand on an NFT.
October 13, 20223 yr Author 11 minutes ago, we_gotta_believe said: Lung, skin, liver cancers? Sure. But brain cancer is a tougher link to establish. Maybe harder to establish, but it seems pretty intuitive that breathing large volumes of noxious chemicals through your nose could cause issues with your brain, as there are tiny passages leading to your brain through your nose, not to mention that anything inhaled can get into your bloodstream. From there, anything can happen. Anecdotally but seemingly relevant, my girlfriend is actually visiting a former coworker today who just came down with some rare brain cancer (astrocytoma) that is potentially inoperable. It's really sad, because she's only in her early 30s and has three young children to care for. It's anyone's guess right now as to what caused it, but she was apparently doing a job installing epoxy flooring awhile and my gf said she was working for some smalltime, local service and doesn't think she was wearing any protective equipment like a respirator when she was doing the work. The rapid onset of the disease is what seems most striking about it. They're currently starting radiation and chemotherapy treatments while seeking guidance from neurosurgeons in Pittsburgh and Indianapolis to see if the tumor can be removed to any extent. I don't know, but the potential for something inhaled to cause brain tumors doesn't seem too far-flung.
October 13, 20223 yr 9 minutes ago, EaglesRocker97 said: If people don't have any money, why is demand so high? Demand for what?
October 13, 20223 yr 1 minute ago, EaglesRocker97 said: Maybe harder to establish, but it seems pretty intuitive that breathing large volumes of noxious chemicals through your nose could cause issues with your brain, as there are tiny passages leading to your brain to your nose, not to mention that anything inhaled can get into your bloodstream. From there, anything can happen. Anecdotally but seemingly relevant, my girlfriend is actually visiting a former coworker today who just came down with some rare brain cancer (astrocytoma) that is potentially inoperable. It's really sad, because she's only in her early 30s and has three young children to care for. It's anyone's guess right now as to what caused it, but she was apparently doing a job installing epoxy flooring awhile and my gf said she was working for some smalltime, local service and doesn't think she was wearing any protective equipment like a respirator when she was doing the work. The rapid onset of the disease is what seems most striking about it. They're currently starting radiation and chemotherapy treatments while seeking guidance from neurosurgeons in Pittsburgh and Indianapolis to see if the tumor can be removed to any extent. I don't know, but the potential for something inhaled to cause brain tumors. Science says no. Blood brain barrier is very good at keeping such things out of the cns. Nose not a path - its actually only the eyes that offer a path to the cns via the optic nerve/chiasm Its human nature to assign a blame to such things but intuition doesnt cut it
October 13, 20223 yr Author 7 minutes ago, ToastJenkins said: Demand for what? Seems like it's pretty much across the board: Oil/gas, housing/industrial real-estate, processed foods, airfare, veterinary services, just to name a few. 6 minutes ago, ToastJenkins said: Science says no. Blood brain barrier is very good at keeping such things out of the cns. Nose not a path - its actually only the eyes that offer a path to the cns via the optic nerve/chiasm Its human nature to assign a blame to such things but intuition doesnt cut it Admittedly out of my wheelhouse, but it if the eyes offer a pathway, and someone is not wearing protection over their eyes, that would seem to be a route, wouldn't it? As far as nasal passages go, I only did a cursory search, but I found this interesting: Quote Although discussed only briefly in the review, the potential for transnasal delivery of drugs into the CNS is also an interesting, and in some instances possibly a quicker and easier approach to implement and overcome this development challenge. We believe the research supporting transnasal delivery into the CNS and thereby bypassing the BBB requires further discussion and clarification of the points raised in the review. The review article refers to a paper from 1971 stating that the close connection between the olfactory bulb and the cerebrospinal fluid (CSF) offers a potential route for nasally delivered drugs to the CSF, provided the drug is able to cross the nasal epithelium and the arachnoid membrane.2 While nose-to-CSF transport has been shown in animals and even in humans, this is not the only and certainly not the most important or promising, transport route into the CNS via the nose.3, 4, 5 A recent research paper and two review papers on the method of transport and the animal studies conducted conclude that both small and large molecules can pass rapidly from the nose into the brain along olfactory nerves and into the brain and brain stem along branches of the first and second trigeminal nerve structures, without primarily passing via the CSF.3, 4, 5 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652706/#:~:text=A recent research paper and,and second trigeminal nerve structures Quote Ken Saladin · Follow Former professor of histology (microscopic anatomy)Upvoted by Michael Soso , BA Berkeley Physiology/Biophysics 1967, PhD Neurophysiology UW 1975 and MD Stanford 1979, 30 years on U Pitt … There are tiny passages from your nose to your brain for the nerves of smell, but none large enough for an insect to pass through. There are some parasitic amoebae, however, that can infect the brain by this route. People who get water in their nose from swimming or other activities occasionally get fatal brain infections this way, but it’s pretty rare. https://www.quora.com/Can-an-insect-crawl-into-my-brain-via-the-nose
October 13, 20223 yr 24 minutes ago, ToastJenkins said: Science says no. Blood brain barrier is very good at keeping such things out of the cns. Nose not a path - its actually only the eyes that offer a path to the cns via the optic nerve/chiasm Its human nature to assign a blame to such things but intuition doesnt cut it Some interesting animal data on the effects of TCDD on brain cells in a mouse model: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0089811#:~:text=Although TCDD does not efficiently,27]%2C [28]. Not enough to prove a point either way here, but it does discuss the BBB in the discussion section. Kinda interesting article. That being said I don't think GBM, the type of cancer Beau died from, is one that is super associated with toxin exposures from my (limited) understanding. I think it's mostly radiation, genetic conditions and bad luck. At least based on our current understanding.
October 13, 20223 yr Note you are looking at hupotheses that are 50 years old and largely rejected to get meaningful ocular exposure you pretty much have to inject the eye or at least get a significant direct splash therr was a ton of similar work hypothesizing that pregnant women could get embryonic exposure from their partners ejaculate. Every experiment showed not
October 13, 20223 yr 3 minutes ago, DEagle7 said: Some interesting animal data on the effects of TCDD on brain cells in a mouse model: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0089811#:~:text=Although TCDD does not efficiently,27]%2C [28]. Not enough to prove a point either way here, but it does discuss the BBB in the discussion section. Kinda interesting article. That being said I don't think GBM, the type of cancer Beau died from, is one that is super associated with toxin exposures from my (limited) understanding. I think it's mostly radiation, genetic conditions and bad luck. At least based on our current understanding. Gliomas tend to be very aggressive and very fatal sadly genetics and bad luck seem to be strongest correlates. There is a spontaneous dog model for gliomas iirc
October 13, 20223 yr 8 minutes ago, ToastJenkins said: Note you are looking at hupotheses that are 50 years old and largely rejected to get meaningful ocular exposure you pretty much have to inject the eye or at least get a significant direct splash therr was a ton of similar work hypothesizing that pregnant women could get embryonic exposure from their partners ejaculate. Every experiment showed not Reminds of the concerns early on in the pandemic about contracting covid via conjunctivitis, people initially wearing goggles, etc. Never really made sense to me, but some docs were convinced it happened to them because of how diligent they claimed they were with masking. Turns out, they just likely slipped up like everyone else.
October 13, 20223 yr 4 minutes ago, ToastJenkins said: Gliomas tend to be very aggressive and very fatal sadly genetics and bad luck seem to be strongest correlates. There is a spontaneous dog model for gliomas iirc Yup, and unfortunately pretty common as far as brain tumors go. Same cancer that got McCain and Ted Kennedy I believe. Now if they could show data that the dioxins led to BBB disruption then I could buy a correlation. But you'd think if that existed it would be common knowledge by now. BBB permeability studies aren't that hard to do in animal models. Used to do em in rats when I was in med school.
October 13, 20223 yr 1 hour ago, Ipiggles said: You can be empathetic to a person for having personal issues that many also go through, and still be critical of the position they are/were in - because of poor choices they made/make. A guy like Hunter, with his family and the money thrown at him? You could say he was very priviledged in life, compared to most, and what has HE done with the head start he was given in life? I dont begrudge anyone for what money they have, or make, or inherited. Life is /was never "fair/equal" we all start out with different circumstances, I wont hold that against anyone. I dont get upset when someone is wealthy, unlike some in here who get really jealous of really wealthy people. However, I dont have respect for a person who is /was so privildeged. I look realistically with how and where a person starts out their life and where they end up. Someone whose family was very wealthy, shipped off to private school, then college education paid for, including a stint at Yale, with his Families connections gets high paying jobs thrown at him? With all that going for him? Nah he owns his loserness. I have more respect for a person who climbs out of poverty and builds something with their life with very little given to them, VS. anyone who were/are very priviledged and just didn't screw it up along the way. I have no respect for those who were priviledged and end up like Hunter Biden. TLDR. The compassion I’m talking about here is mostly for a father that lost one son to cancer and another to addiction.
October 13, 20223 yr 2 minutes ago, Tnt4philly said: TLDR. The compassion I’m talking about here is mostly for a father that lost one son to cancer and another to addiction. I have compassion for anyone losing a loved one. I can also believe Joe Biden was not a good father.
October 13, 20223 yr 1 minute ago, Ipiggles said: I have compassion for anyone losing a loved one. I can also believe Joe Biden was not a good father. It’s mot for me to judge wether someone is a good father or not. I have my own fatherhood to question and I’m sure Biden questions his as well. Addiction couldn’t care less who has good or bad parent or how much money they have. I know too many stories of kids from all walks of life who have fallen to some sort of addiction.
October 13, 20223 yr 5 minutes ago, Ipiggles said: I can also believe Joe Biden was not a good father.
October 13, 20223 yr 1 hour ago, HazletonEagle said: Oh wow.... President Biden erroneously said that his son, Beau, "lost his life in Iraq" during a speech in Colorado on Wednesday. "I say this as a father of a man and won the Bronze Star, the conspicuous service medal, and lost his life in Iraq," Biden said. Beau died of brain cancer in 2015. He went on to say that though he can’t prove it, he believes that the cancer was caused by being exposed to burn pits while in Iraq.
October 13, 20223 yr 4 minutes ago, Tnt4philly said: It’s mot for me to judge wether someone is a good father or not. I have my own fatherhood to question and I’m sure Biden questions his as well. Addiction couldn’t care less who has good or bad parent or how much money they have. I know too many stories of kids from all walks of life who have fallen to some sort of addiction. Addiction can hit anyone, we agree. Also think Joe is /was not a good father. But many aren't. There are worse I am sure.
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