20 minutes ago, Procus said:

Everybody wants to penalize negative behavior unless it's their own negative behavior.  I'm sure if we dig underneath your fingernails, we could find plenty of negative behavior to penalize.

I used to smoke. Would have paid more for insurance if I wanted to continue. I'm not poor and understand decisions have consequences.

11 minutes ago, Dawkins 20 said:

I think this is the first time. He almost missed a game earlier in the year when he simultaneously injured both ankles. 

Quote

The discussion about Wentz's vaccination status stemmed from him being a close contact during training camp. He was placed on the reserve/COVID-19 list. Other Colts players placed on the list during training camp were: Ryan Kelly, Zach Pascal, Eric Fisher, Xavier Rhodes, T.J. Carrie, Julien Davenport and Al-Quadin Muhammad.

https://www.indystar.com/story/sports/nfl/colts/2021/12/28/colts-quarterback-carson-wentz-placed-covid-19-list-what-we-know/9035637002/

https://www.cbc.ca/news/science/smoking-won-t-help-teens-lose-weight-may-stunt-growth-study-1.718537#:~:text=March 24%2C 2008-,Smoking cigarettes won't help teenage girls lose weight%2C but,centimetres shorter than non-smokers.

 

 

 

 

 

bam!

26 minutes ago, Procus said:

Everybody wants to penalize negative behavior unless it's their own negative behavior.  I'm sure if we dig underneath your fingernails, we could find plenty of negative behavior to penalize.

that is one strange phrase. 

https://donaldgmcneiljr1954.medium.com/here-in-new-york-the-omicron-variant-is-getting-weird-db6d39058b18
 

 

7 minutes ago, The_Omega said:

https://donaldgmcneiljr1954.medium.com/here-in-new-york-the-omicron-variant-is-getting-weird-db6d39058b18
 

 

What is the "cleavage site mutation" the article speaks of - is it a boob job gone bad?

4 hours ago, mikemack8 said:

Bikini pics of your daughter or GTFO

I have some pics of your mom. Also of you and Kz! at the 'proud boys' parade.

Good enough?

8 minutes ago, Procus said:

What is the "cleavage site mutation" the article speaks of - is it a boob job gone bad?

Glad to see someone actually read it. Makes the hard work I did copying and pasting the link worth it. Anyway, not sure if this helps explain it or not

The spike (S) protein of Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) binds to a host cell receptor which facilitates viral entry. A polybasic motif detected at the cleavage site of the S protein has been shown to broaden the cell tropism and transmissibility of the virus. Here we examine the properties of SARS-CoV-2 variants with mutations at the S protein cleavage site that undergo inefficient proteolytic cleavage. Virus variants with S gene mutations generated smaller plaques and exhibited a more limited range of cell tropism compared to the wild-type strain. These alterations were shown to result from their inability to utilize the entry pathway involving direct fusion mediated by the host type II transmembrane serine protease, TMPRSS2. Notably, viruses with S gene mutations emerged rapidly and became the dominant SARS-CoV-2 variants in TMPRSS2-deficient cells including Vero cells. Our study demonstrated that the S protein polybasic cleavage motif is a critical factor underlying SARS-CoV-2 entry and cell tropism. As such, researchers should be alert to the possibility of de novo S gene mutations emerging in tissue-culture propagated virus strains.

Author summary

SARS-CoV-2 uses its spike (S) protein to enter target cells. Unlike other similar coronaviruses, the nascent S protein has a polybasic cleavage motif and is cleaved by the host protease. We have identified SARS-CoV-2 variants with mutations at the cleavage motif of S protein (S gene mutants) which undergo inefficient proteolytic cleavage, generate smaller plaques, and infect fewer cell lines. Notably, S gene mutants emerged rapidly through SARS-CoV-2 propagation in Vero cells. Since Vero cells are commonly used for SARS-CoV-2 propagation, it is a very real possibility that researchers have performed experiments, screened antivirals, and developed vaccines using SARS-CoV-2 S gene mutants without realizing.

1 hour ago, EaglesRocker97 said:

Sorry if I'm late on this, but wtf is the CDC doing???

Studies showing people are really infectious 2 days before and 3 days after symptomatic/testing positive. Staying isolated for the full 10 days is too long... After symptoms wane, wear a mask for 5 days just to be safe.

IMO it seems like public policy is shifting towards those who are vaccinated/boosted. If you are still unvaxxed, then it's your own fault. The world isn't going to wait any longer. The virus is endemic, might as well learn to live with it. Godspeed.  

11 minutes ago, The_Omega said:

Glad to see someone actually read it. Makes the hard work I did copying and pasting the link worth it. Anyway, not sure if this helps explain it or not

Was hoping it would be more along the lines of this

20 minutes ago, Toastrel said:

I have some pics of your mom. Also of you and Kz! at the 'proud boys' parade.

Good enough?

No, we need you to bring back the classics. 

The stunning change of the narrative is pretty amazing, here. 

2 hours ago, vikas83 said:

3 people in the office are positive. Happy I haven’t been in the office since the 20th. 

what the hell, slacker?

1 hour ago, paco said:

Lose out and miss the playoffs? 

that would be terrible.

 

unfortunately with Jonathan Taylor being the focal point, Ehlinger doesn't have to be particularly good to give them a chance against the Raiders.

then they play Jacksonville to end the season. probably won't matter much who plays QB.

And the narrative shift continues...

 

14 minutes ago, Procus said:

Was hoping it would be more along the lines of this

I just mutated all over that.

😵 what is this thread about again ? 

6 minutes ago, Kz! said:

The stunning change of the narrative is pretty amazing, here. 

They have no intelligent response to posts like this.  Just deflection or references to Trump as a fallback.

3 minutes ago, Procus said:

They have no intelligent response to posts like this.  Just deflection or references to Trump as a fallback.

They also have "well, The Science™ changed."

Joe Rogan is awesome. This is the way I feel being lectured by the slobs in here.

B***h please!  

3 hours ago, Abracadabra said:

Ask those in Singapore or India if there's any indication horse de-wormer might serve as an effective therapeutic. Ignoring the evidence is not the same as it not existing. 

Observational studies without control groups don’t show causation, that shows CORRELATION.

Correlation isn’t evidence that proves that something works.  It’s a starting point that leads to further evaluation to see if there is CAUSATION. 

I can run a study that evaluates all 32 NFL teams that shows that teams that have their QB kneel the ball in the second half are victorious 100% of the time.  
Does this mean that there is evidence that proves that kneeling the ball in the 2nd half causes NFL teams to be win games?   If an nfl team tried employing the strategy of kneeling the ball to start the 3rd quarter, do you think that would lead to them winning the game?  Or does my study simply show correlation between kneeling the football and winning football games.

9 minutes ago, Kz! said:

Joe Rogan is awesome. This is the way I feel being lectured by the slobs in here.

B***h please!  

But the horse paste hurrdurr

2 hours ago, EaglesRocker97 said:

Sorry if I'm late on this, but wtf is the CDC doing???

 

 

Confirming how arbitrary and political their policies have been all along.

20 minutes ago, Alpha_TATEr said:

😵 what is this thread about again ? 

Making wegottabelieve feel like a big boy

lol I bet there's insane overlap between the freaks who go to extreme measures to avoid covid and people with gender studies degrees.