December 28, 20214 yr 5 minutes ago, vikas83 said: Who saw this coming? Oh right, everyone. Thankfully he will still hit the 75% Is this his first trip on the COVID list this year? I swore he was on it once before
December 28, 20214 yr 1 minute ago, mikemack8 said: Is this his first trip on the COVID list this year? I swore he was on it once before He was as a close contact earlier (during camp I think). Didn’t miss a game and didn’t test positive.
December 28, 20214 yr 3 minutes ago, DEagle7 said: If your doctor isn't talking to you regularly about eating healthy foods and exercise you should find a new one. And those are preventatives. Not treatment. Also not things that can be acutely changed unlike vaccine immunity or medications Which is an effective treatment for obesity. Minimizing the amount of fat you store is a treatment towards the severity of which you can get Covid, it's symptoms, and possible death. SARS-CoV-2 infects human adipose tissue and elicits an inflammatory response consistent with severe COVID-19 https://www.biorxiv.org/content/10.1101/2021.10.24.465626v1
December 28, 20214 yr 6 minutes ago, DaEagles4Life said: Which is an effective treatment for obesity. Minimizing the amount of fat you store is a treatment towards the severity of which you can get Covid, it's symptoms, and possible death. SARS-CoV-2 infects human adipose tissue and elicits an inflammatory response consistent with severe COVID-19 https://www.biorxiv.org/content/10.1101/2021.10.24.465626v1 Absolutely obesity plays a big factor in COVID morbidity. But that's more the role of your primary physician than the CDC given you can't fix that quickly and it's a general health management vs specific COVID treatment. Pretty much every disease process is worsened by obesity
December 28, 20214 yr 41 minutes ago, vikas83 said: The only way we will change behavior is through negative consequences. Let insurance companies charge an obesity premium. Everybody wants to penalize negative behavior unless it's their own negative behavior. I'm sure if we dig underneath your fingernails, we could find plenty of negative behavior to penalize.
December 28, 20214 yr 47 minutes ago, mikemack8 said: Is this his first trip on the COVID list this year? I swore he was on it once before I think this is the first time. He almost missed a game earlier in the year when he simultaneously injured both ankles.
December 28, 20214 yr 20 minutes ago, Procus said: Everybody wants to penalize negative behavior unless it's their own negative behavior. I'm sure if we dig underneath your fingernails, we could find plenty of negative behavior to penalize. I used to smoke. Would have paid more for insurance if I wanted to continue. I'm not poor and understand decisions have consequences.
December 28, 20214 yr 11 minutes ago, Dawkins 20 said: I think this is the first time. He almost missed a game earlier in the year when he simultaneously injured both ankles. Quote The discussion about Wentz's vaccination status stemmed from him being a close contact during training camp. He was placed on the reserve/COVID-19 list. Other Colts players placed on the list during training camp were: Ryan Kelly, Zach Pascal, Eric Fisher, Xavier Rhodes, T.J. Carrie, Julien Davenport and Al-Quadin Muhammad. https://www.indystar.com/story/sports/nfl/colts/2021/12/28/colts-quarterback-carson-wentz-placed-covid-19-list-what-we-know/9035637002/
December 28, 20214 yr https://www.cbc.ca/news/science/smoking-won-t-help-teens-lose-weight-may-stunt-growth-study-1.718537#:~:text=March 24%2C 2008-,Smoking cigarettes won't help teenage girls lose weight%2C but,centimetres shorter than non-smokers. bam!
December 28, 20214 yr 26 minutes ago, Procus said: Everybody wants to penalize negative behavior unless it's their own negative behavior. I'm sure if we dig underneath your fingernails, we could find plenty of negative behavior to penalize. that is one strange phrase.
December 28, 20214 yr https://donaldgmcneiljr1954.medium.com/here-in-new-york-the-omicron-variant-is-getting-weird-db6d39058b18
December 28, 20214 yr 7 minutes ago, The_Omega said: https://donaldgmcneiljr1954.medium.com/here-in-new-york-the-omicron-variant-is-getting-weird-db6d39058b18 What is the "cleavage site mutation" the article speaks of - is it a boob job gone bad?
December 28, 20214 yr 4 hours ago, mikemack8 said: Bikini pics of your daughter or GTFO I have some pics of your mom. Also of you and Kz! at the 'proud boys' parade. Good enough?
December 28, 20214 yr 8 minutes ago, Procus said: What is the "cleavage site mutation" the article speaks of - is it a boob job gone bad? Glad to see someone actually read it. Makes the hard work I did copying and pasting the link worth it. Anyway, not sure if this helps explain it or not The spike (S) protein of Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) binds to a host cell receptor which facilitates viral entry. A polybasic motif detected at the cleavage site of the S protein has been shown to broaden the cell tropism and transmissibility of the virus. Here we examine the properties of SARS-CoV-2 variants with mutations at the S protein cleavage site that undergo inefficient proteolytic cleavage. Virus variants with S gene mutations generated smaller plaques and exhibited a more limited range of cell tropism compared to the wild-type strain. These alterations were shown to result from their inability to utilize the entry pathway involving direct fusion mediated by the host type II transmembrane serine protease, TMPRSS2. Notably, viruses with S gene mutations emerged rapidly and became the dominant SARS-CoV-2 variants in TMPRSS2-deficient cells including Vero cells. Our study demonstrated that the S protein polybasic cleavage motif is a critical factor underlying SARS-CoV-2 entry and cell tropism. As such, researchers should be alert to the possibility of de novo S gene mutations emerging in tissue-culture propagated virus strains. Author summary SARS-CoV-2 uses its spike (S) protein to enter target cells. Unlike other similar coronaviruses, the nascent S protein has a polybasic cleavage motif and is cleaved by the host protease. We have identified SARS-CoV-2 variants with mutations at the cleavage motif of S protein (S gene mutants) which undergo inefficient proteolytic cleavage, generate smaller plaques, and infect fewer cell lines. Notably, S gene mutants emerged rapidly through SARS-CoV-2 propagation in Vero cells. Since Vero cells are commonly used for SARS-CoV-2 propagation, it is a very real possibility that researchers have performed experiments, screened antivirals, and developed vaccines using SARS-CoV-2 S gene mutants without realizing.
December 28, 20214 yr 1 hour ago, EaglesRocker97 said: Sorry if I'm late on this, but wtf is the CDC doing??? Studies showing people are really infectious 2 days before and 3 days after symptomatic/testing positive. Staying isolated for the full 10 days is too long... After symptoms wane, wear a mask for 5 days just to be safe. IMO it seems like public policy is shifting towards those who are vaccinated/boosted. If you are still unvaxxed, then it's your own fault. The world isn't going to wait any longer. The virus is endemic, might as well learn to live with it. Godspeed.
December 28, 20214 yr 11 minutes ago, The_Omega said: Glad to see someone actually read it. Makes the hard work I did copying and pasting the link worth it. Anyway, not sure if this helps explain it or not Was hoping it would be more along the lines of this
December 28, 20214 yr 20 minutes ago, Toastrel said: I have some pics of your mom. Also of you and Kz! at the 'proud boys' parade. Good enough? No, we need you to bring back the classics.
December 28, 20214 yr 2 hours ago, vikas83 said: 3 people in the office are positive. Happy I haven’t been in the office since the 20th. what the hell, slacker?
December 28, 20214 yr 1 hour ago, paco said: Lose out and miss the playoffs? that would be terrible. unfortunately with Jonathan Taylor being the focal point, Ehlinger doesn't have to be particularly good to give them a chance against the Raiders. then they play Jacksonville to end the season. probably won't matter much who plays QB.
December 28, 20214 yr 14 minutes ago, Procus said: Was hoping it would be more along the lines of this I just mutated all over that.
December 28, 20214 yr 6 minutes ago, Kz! said: The stunning change of the narrative is pretty amazing, here. They have no intelligent response to posts like this. Just deflection or references to Trump as a fallback.
December 28, 20214 yr 3 minutes ago, Procus said: They have no intelligent response to posts like this. Just deflection or references to Trump as a fallback. They also have "well, The Science™ changed."
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