October 20, 20223 yr F'ed up run today. Felt like ass before I even started, and it's a challenging route to begin with because much of the first mile, before I get my 2nd wind, is up hill, but I finally started to settle in and get a little more comfortable when I hear something coming up behind me, turn around and there's a snarling, snapping Pitbull coming through a yard toward me. That f'er chased me down the street and was lunging at me when I somehow stomped it's head down into the pavement. Thankfully it then turned around and ran back home. The adrenaline had me feeling ok for another mile or so but then it started wearing off and I had to stop and walk for a little bit, which I never do. I was tempted to go light into the owner of the dog but didn't really want to have to deal with the dog again. Pissed me off.
October 20, 20223 yr 25 minutes ago, The_Omega said: F'ed up run today. Felt like ass before I even started, and it's a challenging route to begin with because much of the first mile, before I get my 2nd wind, is up hill, but I finally started to settle in and get a little more comfortable when I hear something coming up behind me, turn around and there's a snarling, snapping Pitbull coming through a yard toward me. That f'er chased me down the street and was lunging at me when I somehow stomped it's head down into the pavement. Thankfully it then turned around and ran back home. The adrenaline had me feeling ok for another mile or so but then it started wearing off and I had to stop and walk for a little bit, which I never do. I was tempted to go light into the owner of the dog but didn't really want to have to deal with the dog again. Pissed me off. Call animal control
October 20, 20223 yr 3 hours ago, The_Omega said: F'ed up run today. Felt like ass before I even started, and it's a challenging route to begin with because much of the first mile, before I get my 2nd wind, is up hill, but I finally started to settle in and get a little more comfortable when I hear something coming up behind me, turn around and there's a snarling, snapping Pitbull coming through a yard toward me. That f'er chased me down the street and was lunging at me when I somehow stomped it's head down into the pavement. Thankfully it then turned around and ran back home. The adrenaline had me feeling ok for another mile or so but then it started wearing off and I had to stop and walk for a little bit, which I never do. I was tempted to go light into the owner of the dog but didn't really want to have to deal with the dog again. Pissed me off. F that, and yeah call animal control.
October 28, 20223 yr 10 hours ago, DaEagles4Life said: Next to nothing here the mouse immune system is completely different. We can cure all sorts of cancer in those mice. Hasnt translated for many reasons.
October 28, 20223 yr 42 minutes ago, ToastJenkins said: Next to nothing here the mouse immune system is completely different. We can cure all sorts of cancer in those mice. Hasnt translated for many reasons. Mice share around 75-80% the same gene makeup as humans. The study has nothing to do with cancer, it has to do with aging which is a Sinclair's work.
October 28, 20223 yr 23 minutes ago, ToastJenkins said: They argue its suppressing cancer there. Mouse isnt a good translation model. They argue or studies show? And the point of the study was about aging not cancer and that is what they found from the study.
October 28, 20223 yr 28 minutes ago, ToastJenkins said: They argue its suppressing cancer there. Mouse isnt a good translation model. This study says otherwise https://www.sciencedaily.com/releases/2018/01/180118142647.htm A new study is helping to answer a pressing question among scientists of just how close mice are to people when it comes to researching cancer. The findings reveal how mice can actually mimic human breast cancer tissue and its genes, even more so than previously thought, as well as other cancers including lung, oral and esophagus.
October 28, 20223 yr 12 minutes ago, DaEagles4Life said: They argue or studies show? And the point of the study was about aging not cancer and that is what they found from the study. Argue. Its a hypothesis based on data. But One possible conclusion in a different model.
October 28, 20223 yr 30 minutes ago, DaEagles4Life said: This study says otherwise https://www.sciencedaily.com/releases/2018/01/180118142647.htm A new study is helping to answer a pressing question among scientists of just how close mice are to people when it comes to researching cancer. The findings reveal how mice can actually mimic human breast cancer tissue and its genes, even more so than previously thought, as well as other cancers including lung, oral and esophagus. 2018. Has it gone anywhere? i am telling you man people do entire phd thesis on these things and while they can be informative the genetic simularities arent where it matter. Timing and expression patterns are the key. Look up toll like receptors alone (TLR) and people have been trying to develop therapies for decades with nothing to show for it
October 28, 20223 yr Ran past a guy today who was jogging while juggling 3 bowling pins. He appeared to be keeping a decent pace too. True story.
October 28, 20223 yr 19 minutes ago, The_Omega said: Ran past a guy today who was jogging while juggling 3 bowling pins. He appeared to be keeping a decent pace too. True story. I ran a 5k a few years back and there was a dude who was juggling while running it
October 28, 20223 yr 4 minutes ago, mikemack8 said: I ran a 5k a few years back and there was a dude who was juggling while running it I'm just trying to make it back to the car, I'm not looking to add other challenges along the way.
October 28, 20223 yr 3 hours ago, ToastJenkins said: 2018. Has it gone anywhere? i am telling you man people do entire phd thesis on these things and while they can be informative the genetic simularities arent where it matter. Timing and expression patterns are the key. Look up toll like receptors alone (TLR) and people have been trying to develop therapies for decades with nothing to show for it Got it. Cancer should be cured overnight with the amount of red tape with studies and human trials, 4 years is a blink of an eye concerning this type of work. The point of the study had nothing to do with cancer but aging and in theory it makes sense. Autophagy breaks down and destroys senescent cells, which have shown to advance cancer cells. 1 hour ago, The_Omega said: Ran past a guy today who was jogging while juggling 3 bowling pins. He appeared to be keeping a decent pace too. True story. Where do you run lol
October 28, 20223 yr 11 minutes ago, DaEagles4Life said: Got it. Cancer should be cured overnight with the amount of red tape with studies and human trials, 4 years is a blink of an eye concerning this type of work. The point of the study had nothing to do with cancer but aging and in theory it makes sense. Autophagy breaks down and destroys senescent cells, which have shown to advance cancer cells. Where do you run lol Good strawman. Make sure you dont learn anything in all of this
October 28, 20223 yr 5 minutes ago, ToastJenkins said: Good strawman. Make sure you dont learn anything in all of this From you, nope. I'll trust the guy that the Tweet came from.
October 28, 20223 yr An academic claiming stuff so he can keep getting grants? Good luck with that. Funny how they are never wrong… except he is there as they claimed it was aging but the hypothesis didnt hold. So it must be cancer!!
October 28, 20223 yr 8 minutes ago, ToastJenkins said: An academic claiming stuff so he can keep getting grants? Good luck with that. Funny how they are never wrong… except he is there as they claimed it was aging but the hypothesis didnt hold. So it must be cancer!! Damn you Harvard for hiring him and wasting your money
October 28, 20223 yr 23 minutes ago, LacesOut said: I don’t know what’s worse at the gym: teenaged boys who smell and don’t have any gym etiquette, OR, elderly people who smell and don’t have any gym etiquette!! Elderly.
November 20, 20223 yr Ran in a Girls on the Run 5K with my 8-year-old daughter today. Didn’t get to condition leading up to the race as much as I would’ve liked, and she missed the last week of practices due to being sick, but in the end we fared well and finished in 41:09.70. It was her first 5K ever and she loved it. Looks like I’m going to be a runner now because we’re already planning to run after school Tuesday night.
November 21, 20223 yr Couple weeks back into weight training now that golf season is over. Peleton and that should keep me crippled until spring
November 22, 20223 yr 36 minutes ago, LacesOut said: My most recent and future workouts: Friday was Shoulders Saturday was Back Sunday was Chest Monday is Off/rest day Tuesday will be Legs Wednesday will be Arms Thursday - Off/rest day. Turkey and stuffing and mashed taters and sweet taters and just a lot of FOOD!! Sunday - right arm Monday - right arm Tuesday - right arm Wednesday - right arm Thursday - right arm Friday - right arm Saturday - "the stranger"
November 22, 20223 yr 2 hours ago, Arthur Jackson said: Sunday - right arm Monday - right arm Tuesday - right arm Wednesday - right arm Thursday - right arm Friday - right arm Saturday - "the stranger" Give yourself some strange and change hands
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